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访 问 量:4289美国戴安 货号:054993描述:色谱柱ProPac WCX-10 Analytical Column (4 x 250 mm)
ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency separations of protein variants. A hydrophilic layer prevents unwanted secondary interactions. A grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.
• Characterization and quality control assessment of monoclonal antibodies and other proteins
• Unequalled resolution
• High-efficiency separations with excellent sample recovery
• Unmatched column-to-column and lot-to-lot reproducibility
• Useful for characterization of related protein variants (e.g.,deamidation and MAb lysine truncation variants)
• Highly-efficient peaks with excellent sample recovery
• Available in different dimensions and formats for flexibility in method development
The ProPac SCX-10 is a strong cation exchange column with sulfonate functional groups. The ProPac WCX-10 has a carboxylate functional group. Both are based on 10 μm nonporous,polymeric beads and coated with a proprietary hydrophilic layer. All ProPac columns are manufactured and tested under the strictest specifications, resulting in unmatched column-to column and lot-to-lot reproducibility. Dionex also offers ProPac columns as a lot select package: either three columns from one lot or three columns from three different lots, to assist quality control scientists in method validation.